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    Bupropion

    Aliases: wellbutrin, zyban, amfebutamone

    Categories

    stimulant habit-forming

    Summary

    A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.

    Onset, Duration & After-effects

    • Onset: 15-90 minutes
    • Duration:
      • Metabolites: 20-37 hours
      • Parent: 11-21 hours
    • After-effects: 1-6 hours

    Studies