Clomethiazole
Categories
depressant
research-chemical
habit-forming
tentative
Summary
Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.
⚠️ WARNING: The normal amount in capsules is 192mg's. Treat this more as a barbiturate than a benzodiazepine, as the toxicology for this substance is rather lacking.
Dose Information
Onset, Duration & After-effects
- Onset:
15-40 minutes
- Duration:
5-8 hours
- After-effects:
1-16 hours
Effects
- Anxiolytic
- Sedative
- Muscle Relaxant
- Amnesia
- Dystaxia
- Hypnotic