LSD is a popular psychedelic with a relatively long history of use and research, and as such is known to be relatively safe despite its extremely high potency. It is the archetypical psychedelic to which all others are compared, and remains in popular usage.
⚠️ These doses are for pure LSD, note that tabs are often rather a lot weaker than they are advertised.
These combinations are considered extremely harmful and should always be avoided.
lithium: There is a large number of reports indicating a high seizure and psychosis risk from this combination.
There is considerable risk of physical harm when taking these combinations, they should be avoided where possible.
tramadol: Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.
These combinations are not usually physically harmful, but may produce undesirable effects.
amphetamines: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
cannabis: Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.
cocaine: Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences