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    Midazolam

    Categories

    benzodiazepine habit-forming depressant

    Summary

    A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.

    ⚠️ AVOID: All other CNS depressants.

    Dose Information

    Onset, Duration & After-effects

    • Onset:
      • Insufflated: 1-5 minutes
      • Intramuscular: 10-20 minutes
      • Intravenous: 0-1 minutes
      • Oral: 10-40 minutes
      • Rectal: 15-25 minutes
    • Duration: 4-8 hours
    • After-effects: 1-12 hours

    Effects