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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2C-C Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 28 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: 2cc

    Summary PsychonautWiki

    4-Chloro-2,5-dimethoxyphenethylamine (commonly known as 2C-C) is a lesser-known psychedelic substance of the phenethylamine class that produces psychedelic effects when administered. It is a member of the 2C-x family of psychedelic phenethylamines, all of which were derived from the systematic modification of the mescaline molecule.

    Perspectives

    “The nature of the experience itself resembled other explorations with 2C-C- it was marked with a certain latent energy, like heat rising off of hot asphalt. It rippled with fire and electricity like a transformer explosion, and was adorned with bright pulsing and flashing visuals, architectural and structural and artificial, with a focus on radial and concentric forms conforming to straight, careful frameworks.”

    “This is longer lived than 2C-B, and there is a longer latency in coming on. It took an hour and a half, or even two hours to get there. It had a slight metallic overtone.”

    Dose Information Drugs.Wiki

    ROA Light Common Strong Heavy
    Oral 15-25mg 25-35mg 35-55mg 55mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — Drugs.Wiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki Erowid

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-45 min 45-90 min 2-3 hrs 1-3 hrs 4-12 hrs 4-7 hrs
    Insufflated 4-19 min 30-60 min 2-3 hrs 1-3 hrs 2-6 hrs 4-8 hrs

    Effect Profile

    135 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 99 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    external hallucinations internal hallucinations color enhancement autonomous entities drifting tracers +4 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations personal bias suppression time distortion +1 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea temperature regulation suppression muscle tension teeth grinding increased heart rate
    Stimulant 6.9
    Strong+ 7/10

    Strong anxiety/jitters and stimulation with moderate euphoria and focus

    Stimulation / Energy ×3
    9
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    euphoria
    Focus / Productivity ×2
    7
    analysis enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate teeth grinding muscle tension

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    General psychedelic tolerance pattern: rapid tolerance after a single session, partial decay in ~3 days, near‑baseline by ~1–2 weeks for most users. Data are largely anecdotal by extrapolation from 2C‑B, mescaline, and class‑wide sources.

    Effects Erowid Bluelight

    Aggregated from 99 Erowid and 36 Bluelight experience reports

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect, something witnessed, or "did not happen" count too). Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 76

    65.2% 78%
    48.9% 86%
    48.9% 90%
    39.2% 81%
    37.8% 87%
    35.5% 85%
    35.5% 84%
    33.3% 84%
    32.6% 82%
    31.8% 83%
    27.4% 88%
    25.0% 88%
    22.2% 88%
    22.2% 89%
    22.2% 84%
    20.7% 83%
    Auditory Effects 20.0% 80%
    19.4% 83%
    19.4% 77%
    19.4% 82%

    Adverse Effects 41

    36.1% 70%
    32.6% 83%
    32.6% 72%
    26.6% 80%
    14.0% 80%
    13.9% 85%
    13.9% 83%
    11.1% 88%
    11.1% 82%
    10.4% 75%
    8.9% 70%
    8.3% 80%
    8.3% 80%
    8.3% 82%
    8.3% 79%
    8.3% 78%
    8.3% 92%
    7.4% 71%
    7.1% –
    5.6% 75%

    Combinations TripSit

    Cross-Check 2C-C with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 6 positive 1 neutral 1 cautionary visit
    Quite Pleasant positive exp #25372

    Substance - 2C-C (2,5-dimethyoxy-4-chlorophenethylamine) Experience - First time Setting - my basement Many of my past reports have shown I am favorable to 2C-I. It was the first phenethylamine I ever tried. I fell in love with 2C-I and wanted to see what other experiences the 2C family had to offer.

    Matt Himself · 36 mg oral
    An Exfoliating Mud-bath for the Soul neutral exp #34841

    Dose: 2C-C powder was measured at a dose of 50mg and taken orally in a gelatin capsule. Duration: The full-blown experience lasted about 4 hours, with 3 additional hours of after effects.

    Nog · 50 mg oral
    Good Fun Trip positive exp #82208

    Tried for the first time last night. Had 125mg and me and my mate went through the lot doin 15 or 20mg lines, can't remember! Tracers looked fookin amazing, and there was loads of little particles zipping about - shiny stuff like tin foil looked cool and zippy aroundish too :-) .

    Naboo The Enigma · 50 mg insufflated
    Gorgeous and Deeply Satisfying positive exp #111270

    A Gorgeous and Deeply Satisfying Experience This was my first experience with 2C-C. I had been putting it off for a while even though I had been really wanting to explore it and other phenethylamines more simply because my supply of them is much more limited than of the tryptamines or lysergamides, so I've been wanting...

    Kaleida · 33 mg oral / repeated smoked / 8 carts. inhaled
    First Trials positive exp #75345

    I wanted to compare the structural activity of the lesser-known phenethylamine 2C-C to that of itΒ’s closely-related neighbor, 2C-B, a compound that I personally have always enjoyed. I placed an order and when my sample arrived, it appeared more or less identical to 2C-B: a fluffy, finely-textured white powder.

    LucidStudies · 20 mg oral / 30 mg oral
    Beautiful, Rewarding, and Underrated positive exp #48532

    In this report, I try to provide a very thorough and accurate description of the nature of 2C-C. If you donΒ’t want to read a detailed description of the effects, then you should just skip to the second to last paragraph Β“Summery of my 2C-C experienceΒ” for a concise summery of its impression on me.

    Cactushead · 20 mg oral
    Tripping at Settler's Rock positive exp #25426

    July 16, 2003 I must begin by saying that my actions during this trip were the stupidest and most irresponsible of anything I have ever done while on a psychedelic. What I did should be an example to all of what not to do when you are tripping for the first on a high dose of an experimental substance.

    Morninggloryseed
    Set and Setting Sensitive Psychosis cautionary exp #52261

    Space and time: New York City, March 2006 A strong dose of 2C-C in a public setting resulted in an overwhelming and paranoid experience. In retrospect, guinea pigging a new drug outside of a careful and private setting was very foolish and the ultimate reason that this trip went awry.

    Trippopotamus · 40 mg oral / 30 mg oral / oral
    Bluelight 8 threads 8 neutral visit
    2c C First Time Quite Pleasant neutral

    Substance – 2C-C (2,5-dimethyoxy-4-chlorophenethylamine) Experience – First time Setting – my basement Many of my past reports have shown I am favorable to 2C-I. It was the first phenethylamine I ever tried. I fell in love with 2C-I and wanted to see what other experiences the 2C family had to offer.

    2c C Second Time 36mg neutral

    2-CC, 36mg Some quick background about my experience with hallucinagens - mushrooms, LSD, 4-ACO, 5MEO-DMT, salvia, and most recently 2-CC. Approx. two weeks ago I tried 2-CC for the first time, did 33mg via pill and thoroughly enjoyed it. I dosed and then went into the woods for a day of hiking and relaxing.

    36 mg mentioned in the thread; auto-extracted, unverified
    2c C Second Time Good Vibrations neutral

    Forgive the cheesy title 'good vibrations'. Not an original phrase to use in relation to psychedelia, but it seemed an appropriate one, given the focus of the peak of the experience.

    2c C 33 Mg First Time A Gorgeous And Deeply Satisfying Experience neutral

    This was my first experience with 2C-C. I had been putting it off for a while even though I had been really wanting to explore it and other phenethylamines more simply because my supply of them is much more limited than of the tryptamines or lysergamides, so I've been wanting to make sure I wait for the perfect times t...

    33 mg mentioned in the thread; auto-extracted, unverified
    2c C First Time My What A Slow And Shapely Triangle But Oh My Legs neutral

    My first trip report here, this, as well as being my first time with 2C-C. I'm sure I've given too little or too much detail on various aspects. Please do ask questions, if anything needs fleshing out. Dose, substance, route I took 36 mg (+/- 1 mg) of 2C-C, orally.

    36 mg mentioned in the thread; auto-extracted, unverified
    2c C First Time Tripping At Settlers Rock neutral

    July 16, 2003 Fifty-milligrams of 2,5-dimethoxy-4-chlorophenethylamine hydrochloride I must begin by saying that my actions during this trip were the stupidest and most irresponsible of anything I have ever done while on a psychedelic.

    2c C Approx 150mg 1st Trip neutral

    Ok if you want to skip the boring preface part just got down a bit and start reading from The Trip. Preface: Ok so 150mg sounds a bit extreme and possibly foolish. It's possible I may have built up some tolerance from taking 2C-C the previous night. So I do not know if 150mg would be too much or okay for someone else.

    150 mg mentioned in the thread; auto-extracted, unverified
    Dose.wiki 2 reports 1 positive 1 neutral visit
    Novel Pleasantry 40 mg oral in gel cap positive

    Overall, this is one of my favorite drugs now. I love the powerful visuals, I love the lucidity and warm euphoria, I love the electric body buzzing. Good shit.

    by nervewing
    Spitfire 30 mg intransal neutral

    2C-C dosed intranasally has a similar effect profile to other intranasally dosed 2C-x compounds- namely greater potency, faster comeup, shorter duration, and extreme pain upon dosing. 2C-C however was particularly unpleasant to consume. It had roughly the…

    by nervewing

    Bluelight Reference Guide Bluelight

    β˜› Official ☚ The Big & Dandy 2C-C Thread - V2: Chlory hallelujah

    External Information Links: Erowid 2C-C Vault (experience reports) PIHKAL Entry on 2C-C Wikipedia entry Link to previous thread Continue discussion, you rapscallions.

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #22: 2C-C

    “This is longer lived than 2C-B, and there is a longer latency in coming on. It took an hour and a half, or even two hours to get there. It had a slight metallic overtone.”

    β€” Alexander Shulgin, PiHKAL (with 20 mg)
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 2C-C, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "2C-C (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Dose & duration (reference)
    2C-C: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Insufflated dose (mg): threshold 2
    
    Insufflated duration: onset 4-19m Β· come-up 0.5-1h Β· peak 2-3h Β· offset 1-3h Β· total 4-8h Β· after-effects 2-6h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.