3,4-CFPP
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 3,4-cfp, 3cl-4f-p, Kleferein, 3-chloro-4-fluoro-piperein
Summary
Very little pharmacological or toxicological data exists. Based on structural similarity to mCPP and TFMPP, this compound likely acts as a non-selective serotonin receptor agonist and serotonin releaser. These phenylpiperazines are notorious for producing nausea, migraines, anxiety, and dysphoria rather than euphoria.
Dose Information
Dose basis. Ranges are compiled from scattered user reports and by analogy to related phenylpiperazines; no formal human data exist. Always allergy test (≈1–2 mg) and use a calibrated milligram scale. Expect more nausea and headache than with classical empathogens; redosing tends to increase adverse effects disproportionately. Evidence quality: anecdotal. Phenylpiperazines can be irritating to mucosa and more likely to cause headaches and nausea when snorted; TFMPP/pFPP reports specifically note sore throat/nasal irritation. Prefer oral route for lower adverse-event rates. Evidence: user reports on piperazines; no CFPP-specific data. Evidence quality: anecdotal. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-50mg | 50-100mg | 100-150mg | 150mg+ |
| Insufflated | 5-15mg | 15-40mg | 40-70mg | 70mg+ |
Sources
Oral
Dose ladder — Drugs.WikiInsufflated
Dose ladder — Drugs.WikiOnset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 20-60 min | 1-3 hrs | 1-2 hrs | 2.33-6 hrs |
| Insufflated | 5-15 min | 1-3 hrs | 1-2 hrs | 2.08-5.25 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate stimulation with mild euphoria, low empathy and sensory enhancement
Strong anxiety/jitters with mild stimulation and euphoria
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Effect glossary — · full glossary
Combinations
Cross-Check 3,4-CFPP with another substanceHelpful Links
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The PsychonautWiki Journal logging app doesn't include every substance. To track 3,4-CFPP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
3,4-CFPP Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 20 · light 20-50 · common 50-100 · strong 100-150 · heavy 150+ Insufflated dose (mg): threshold 5 · light 5-15 · common 15-40 · strong 40-70 · heavy 70+ Oral duration: onset 0.33-1h · peak 1-3h · offset 1-2h · total 2.33-6h · after-effects 1-6h Insufflated duration: onset 5-15m · peak 1-3h · offset 1-2h · total 2.08-5.25h · after-effects 1-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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