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    4-HO-MiPT molecular structure

    4-HO-MiPT Stats & Data

    4-ho Ho-mipt Miprocin 4homipt homipt
    PubChem
    MW232.32
    FormulaC14H20N2O
    LogP2.8
    IUPAC3-[2-[methyl(propan-2-yl)amino]ethyl]-1H-indol-4-ol
    InChIKeyRXKGHZCQFXXWFQ-UHFFFAOYSA-N
    Chemical Class Substituted tryptamine
    Psychoactive Class Psychedelic

    Subjective Effects

    Physical
    • Spontaneous tactile sensations: The 'body high' of 4-HO-MiPT can be described as a pleasurable, warm, soft and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached.
    • Sedation: In terms of its effects on the physical energy levels of the tripper, 4-HO-MiPT is considered by most to be relaxing, stoning and mildly sedating. This sense of sedation is often accompanied by compulsive yawning.
    • Runny nose
    • Watery eyes
    Cognitive

    The cognitive effects of 4-HO-MiPT are described by many as extremely relaxing, profound and stoning in style when compared to other commonly used psychedelics such as LSD or 2C-B which tend to be energetic and stimulating.

    • Enhancement of current mind state
    • Connectivity of thought
    • Feelings of fascination, importance and awe
    • Time distortion
    • Outrospection
    • Déjà vu
    • Removal of cultural filter
    • Feelings of predeterminism
    • Conceptual thinking
    • Direct communication with the subconscious
    • Ego suppression, loss and death
    • Feelings of interdependent opposites
    • Delusions
    • States of unity and interconnectedness
    • Enhancement and suppression cycles: This can be described as constant waves of extremely stimulated and profound thinking which are spontaneously surpassed in a cyclic fashion by waves of general thought suppression and mental intoxication. These two states seem to switch between each other in a consistent loop once every 20 - 60 minutes.
    Sensory
    Auditory
    • Enhancements
    • Distortions
    • Hallucinations
    Visual · Distortions
    • Visual drifting: (Melting, Flowing, Breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, realistic, slow and smooth in motion and static in appearance.
    • Tracers
    • After images
    • Texture repetition
    • Colour shifting
    • Scenery slicing
    Visual · Enhancements
    • Increased visual acuity
    • Enhancement of colour
    • Enhanced pattern recognition
    Visual · Hallucinatory States

    4-HO-MiPT and its various other forms produce a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics.

    • Transformations
    • Internal hallucinations: (Autonomous entities, Settings, sceneries, and landscapes, Alterations in perspective and Scenarios and plots) - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their variations as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, geometry-based in style and almost exclusively of a religious, spiritual, mystical, science fiction or transcendental nature in their overall theme.

    Forked from Subjective Effect Documentation by Josie Kins, July 2014. Via dose.wiki (CC0).

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational 4-HO-MiPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 4-HO-MiPT is a research chemical with very little history of human usage. Anecdotal evidence from those have tried 4-HO-MiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance.

    Effect Profile

    Curated + 71 Reports
    Psychedelic 8.8

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity×3
    10103.9
    Headspace Depth×3
    108.32.3
    Auditory Effects×1
    10102.7
    Body Load / Somatic Effects×1
    10105.5
    Catalog Erowid BlueLight

    Community Effects

    TripSit
    Positive
    visual enhancement euphoria body high music enhancement
    Negative
    nausea body load anxiety

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    LSD
    Psilocybin
    Psilocin
    Mescaline
    DMT
    5-MeO-DMT
    2C-B
    2C-E

    Experience Report Analysis

    Erowid BlueLight
    81 Reports
    34 Single-substance
    2004–2024 Date Range
    59 With Age Data
    27 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid + Bluelight

    Effects aggregated from 71 experience reports (34 single-substance Erowid + 37 Bluelight)

    71 Reports
    146 Effects Detected
    77 Positive
    49 Adverse
    20 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.

    Positive Effects 77

    Visual Distortions 47.9% (95% interval 37 to 59 percent) 78%
    Music Enhancement 45.1% (95% interval 34 to 57 percent) 88%
    Color Enhancement 43.6% (95% interval 33 to 55 percent) 88%
    Visual Trails 37.8% (95% interval 24 to 54 percent) 89%
    Closed-Eye Visuals 36.6% (95% interval 26 to 48 percent) 90%
    Empathy 31.0% (95% interval 21 to 42 percent) 84%
    Stimulation 31.0% (95% interval 21 to 42 percent) 83%
    Surface Breathing 27.0% (95% interval 15 to 43 percent) 84%
    Joy 27.0% (95% interval 15 to 43 percent) 88%
    Introspection 23.9% (95% interval 16 to 35 percent) 80%
    Euphoria 22.5% (95% interval 14 to 34 percent) 93%
    Contentment 21.6% (95% interval 11 to 37 percent) 85%
    Awe 21.6% (95% interval 11 to 37 percent) 79%
    Geometric Imagery 21.6% (95% interval 11 to 37 percent) 86%
    Libido Enhancement 21.6% (95% interval 11 to 37 percent) 84%
    Patterning 18.9% (95% interval 10 to 34 percent) 86%
    Body High 18.3% (95% interval 11 to 29 percent) 86%
    Tactile Enhancement 16.9% (95% interval 10 to 27 percent) 83%
    Melting/flowing 16.2% (95% interval 8 to 31 percent) 85%
    Insight 16.2% (95% interval 8 to 31 percent) 82%

    Adverse Effects 49

    Body Load 40.5% (95% interval 26 to 56 percent) 77%
    Anxiety 38.0% (95% interval 28 to 50 percent) 81%
    Nausea 23.9% (95% interval 16 to 35 percent) 79%
    Muscle Tension 21.1% (95% interval 13 to 32 percent) 78%
    Confusion 18.3% (95% interval 11 to 29 percent) 82%
    Tremor 16.2% (95% interval 8 to 31 percent) 81%
    Paranoia 16.2% (95% interval 8 to 31 percent) 85%
    Thought Disorganization 16.2% (95% interval 8 to 31 percent) 82%
    Jaw Clenching 14.1% (95% interval 8 to 24 percent) 80%
    Temporal Disorientation 10.8% (95% interval 4 to 25 percent) 84%
    Depersonalization 10.8% (95% interval 4 to 25 percent) 80%
    Fear 10.8% (95% interval 4 to 25 percent) 85%
    Motor Impairment 9.9% (95% interval 5 to 19 percent) 77%
    Memory Suppression 9.9% (95% interval 5 to 19 percent) 85%
    Increased Heart Rate 8.8% (95% interval 3 to 23 percent) 70%
    Sweating 8.5% (95% interval 4 to 17 percent) 80%
    Headache 8.4% (95% interval 4 to 17 percent) 80%
    Insomnia 8.1% (95% interval 3 to 21 percent) 80%
    Social Anxiety 5.4% (95% interval 2 to 18 percent) 78%
    Cold Flashes 5.4% (95% interval 2 to 18 percent) 75%
    Show 29 more adverse effects
    Thought Loops 5.4% (95% interval 2 to 18 percent) 80%
    Panic 5.4% (95% interval 2 to 18 percent) 85%
    Restlessness 5.4% (95% interval 2 to 18 percent) 75%
    Libido Suppression 5.4% (95% interval 2 to 18 percent) 82%
    Visual Sharpening 5.4% (95% interval 2 to 18 percent) 90%
    Amnesia 5.4% (95% interval 2 to 18 percent) 88%
    Numbness 5.4% (95% interval 2 to 18 percent) 78%
    Guilt 2.7% (95% interval 0 to 14 percent) 70%
    Gastrointestinal Effects 2.7% (95% interval 0 to 14 percent) 80%
    Auditory Echo 2.7% (95% interval 0 to 14 percent) 80%
    Emotional Lability 2.7% (95% interval 0 to 14 percent) 70%
    Body Temperature Change 2.7% (95% interval 0 to 14 percent) 75%
    Delusion 2.7% (95% interval 0 to 14 percent) 80%
    Dysphoria 2.7% (95% interval 0 to 14 percent) 80%
    Auditory Suppression 2.7% (95% interval 0 to 14 percent) 75%
    Loneliness 2.7% (95% interval 0 to 14 percent) 80%
    Vulnerability 2.7% (95% interval 0 to 14 percent) 75%
    Overwhelm 2.7% (95% interval 0 to 14 percent) 85%
    Pressure 2.7% (95% interval 0 to 14 percent) 80%
    Paranoid Ideation 2.7% (95% interval 0 to 14 percent) 75%
    Emotional Blunting 2.7% (95% interval 0 to 14 percent) 75%
    Bloating 2.7% (95% interval 0 to 14 percent) 75%
    Sadness 2.7% (95% interval 0 to 14 percent) 80%
    Dry Mouth 2.7% (95% interval 0 to 14 percent) 75%
    Ataxia 2.7% (95% interval 0 to 14 percent) 80%
    Back Pain 2.7% (95% interval 0 to 14 percent) 90%
    Pain Enhancement 2.7% (95% interval 0 to 14 percent) 90%
    Disrupted Sleep Architecture 2.7% (95% interval 0 to 14 percent) 75%
    Focus Suppression 2.7% (95% interval 0 to 14 percent) 75%

    Dose-Response Correlation

    How effect frequency changes across dose levels. Whiskers, and the numbers' hover text, give each figure's 95% interval.

    Not drawn, too few reports (a dose tier needs 20): Oral Strong (n=12). Why 20?

    Dosage Distribution

    Dose distribution from experience reports, one dose per report (the first listed). Values above Q3 + 3×IQR are left out as outliers.

    Median: 21.0 mg IQR: 16.0–28.0 mg n=53 2 outliers left out

    Real-World Dose Distribution

    62K Doses

    From 119 individual dose entries. Values above Q3 + 3×IQR are left out as outliers.

    Oral (n=96)

    Median: 20.0mg 25th: 15.0mg 75th: 27.25mg 90th: 30.5mg

    Insufflated (n=13)

    Median: 10.0mg 25th: 6.0mg 75th: 15.0mg 90th: 20.0mg

    Common Combinations

    Most co-occurring substances, as a share of all 81 reports filed under 4-HO-MiPT; whiskers are 95% intervals

    Form / Preparation

    Most common forms and preparations, as a share of the 64 reports that give one; whiskers are 95% intervals

    Body-Weight Dosing

    Dose per kg of body weight, one dose per report (the first listed), from reports giving a weight of 30–250 kg. Values above Q3 + 3×IQR are left out as outliers.

    Median: 0.317 mg/kg IQR: 0.228–0.393 mg/kg n=51 2 outliers left out

    Redose Patterns

    Redosing behavior across 68 reports

    19.1% (95% interval 12 to 30 percent) Redosed
    1.3 Avg Doses
    30m Median Interval
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