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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-AEDB Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • partial dose data
    • duration data present
    • 28 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Psychedelic Stimulant Research-chemical

    Summary dose.wiki

    Practically no human research exists; all parameters are based on scattered user reports of 5-AEDB sold online between 2019-2024 and extrapolation from related benzofurans (5-APB, 5-APDB). Potency appears roughly 60-70% of 5-APB by weight and markedly shorter in duration. Users frequently report pronounced peripheral stimulation (increased heart rate and blood pressure) compared with MDMA, alongside moderate empathogenic warmth and mild visual enhancement.

    Dose Information source not identified

    ROA Heavy
    Oral 130+ mg (NOT ADVISED)
    Heavy
    Sources· no ladder identified

    Oral

    Dose ladder — source not identified

    Onset, Duration & After-effects dose.wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 45-90 min 30-60 min 1.5-3 hrs 1-2 hrs 2-6 hrs 3.75-7.5 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 2.9
    Light+ 3/10

    Strong body load and auditory effects with mild visuals, low headspace

    Visual Intensity ×3
    4
    visual tracers tracers visual acuity enhancement
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    10
    vasoconstriction temperature regulation suppression nausea teeth grinding increased heart rate
    Empathogen 5.4
    Moderate+ 5/10

    Moderate stimulation and sensory enhancement with mild empathy and euphoria

    Empathy / Social Openness ×3
    5
    empathy and prosocial feelings increased sociability
    Euphoria / Mood Elevation ×2
    5
    euphoria mood lift
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    6
    tactile enhancement visual acuity enhancement increased libido
    Stimulant 4.0
    Moderate 4/10

    Strong anxiety/jitters with moderate stimulation, mild euphoria, low focus

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    5
    euphoria mood lift
    Focus / Productivity ×2
    2
    thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate vasoconstriction
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects dose.wiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check 5-AEDB with another substance

    5-AEDB's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 5-AEDB there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    5-AEDB
    Unit
    mg
    Description 
    5-AEDB
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 25 · heavy 130+  (NOT ADVISED)

Oral duration: onset 0.75-1.5h · come-up 0.5-1h · peak 1.5-3h · offset 1-2h · total 3.75-7.5h · after-effects 2-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.