- Acuity suppression
- Amnesia
- Auditory distortion
- Auditory suppression
- Changes in felt bodily form
- Cognitive euphoria
- Compulsive redosing
- Déjà vu
- Depersonalization
- Derealization
- Dizziness
- Double vision
- External hallucinations
- Frame rate suppression
- Geometry
- Headaches
- Information processing suppression
- Internal hallucinations
- Laughter
- Memory suppression
- Motor control loss
- Pattern recognition suppression
- Perception of decreased weight
- Physical euphoria
- Spontaneous tactile sensations
- Suggestibility enhancement
- Tactile suppression
- Thought deceleration
- Unity and interconnectedness
N2O
Aliases: laughing_gas, n20, n2o, nos
Categories
Summary
Nitrous oxide, also known as laughing gas, often inhaled through balloons filled with canisters of the gas.. A short-acting dissociative inhalant with strong visual, mental and auditory effects. Extremely popular especially in combination with other drugs.
Onset, Duration & After-effects
- Onset: 0-1 minutes
- Duration: 1-5 minutes
- After-effects: 15-30 minutes
Effects
- giggling
- mood lift
- euphoria
- sound distortion
- dream like state
- minor to strong hallucinations
- reduction of external stimuli
- analgesia
- buzzing sensation in nerve
- clumsiness
- nausea
- headaches
- numbness in extremities
Known Combinations
These combinations are not usually physically harmful, but may produce undesirable effects.
alcohol: Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.
ghb/gbl: Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.
opioids: Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.
tramadol: Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.
Effects are additive. The combination is unlikely to cause any adverse or undesirable reaction.
lithium: We are unable to find a report of concerns for CNS depression caused by Lithium.
Studies
- Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats
- Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia
- Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency