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    Pentobarbital

    Aliases: nembutal, novopentobarb

    Categories

    depressant habit-forming barbiturate

    Pentobarbital structure

    Summary

    A CNS depressant drug that is of the barbituate class. Typically not used often as it is easier to OD on than benzodiazepines, the new alternative to barbituates. Used often for insomnia, to cause sedation.

    ⚠️ AVOID: All other CNS depressants, also avoid if you have respiratory issues or liver issues as barbiturates are harsh on the liver.

    Dose Information

    Onset, Duration & After-effects

    • Onset:
      • Intramuscular: 10-25 minutes
      • Intravenous: 1 minutes
      • Oral: 15-60 minutes
    • Duration:
      • Intramuscular: 3-4 hours
      • Intravenous: 15-20 hours
      • Oral: 3-4 hours
    • After-effects: 1-36 hours

    Studies